Ichiro Nakashima Selected Research

Acute Disseminated Encephalomyelitis (Postinfectious Encephalomyelitis)

3/2021	Myelin oligodendrocyte glycoprotein-IgG-positive, steroid-responsive combined central and peripheral demyelination with recurrent peripheral neuropathy.
11/2019	Clinical spectrum of inflammatory central nervous system demyelinating disorders associated with antibodies against myelin oligodendrocyte glycoprotein.
8/2018	Rituximab was effective for acute disseminated encephalomyelitis followed by recurrent optic neuritis with anti-myelin oligodendrocyte glycoprotein antibodies.
4/2017	Anti-MOG antibody-positive ADEM following infectious mononucleosis due to a primary EBV infection: a case report.
8/2016	Post-vaccination MDEM associated with MOG antibody in a subclinical Chlamydia infected boy.
10/2015	Clinical features and long-term outcome of a group of Japanese children with inflammatory central nervous system disorders and seropositivity to myelin-oligodendrocyte glycoprotein antibodies.

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Ichiro Nakashima Research Topics

Disease

60	Neuromyelitis Optica (Devic's Disease) 04/2022 - 04/2004
38	Multiple Sclerosis 01/2022 - 11/2002
27	Optic Neuritis (Retrobulbar Neuritis) 01/2022 - 01/2011
20	Demyelinating Diseases (Demyelinating Disease) 12/2021 - 08/2007
11	Myelitis 12/2021 - 01/2011
9	Encephalitis (Encephalitis, Rasmussen) 01/2021 - 01/2017
6	Acute Disseminated Encephalomyelitis (Postinfectious Encephalomyelitis) 03/2021 - 10/2015
5	Infections 01/2021 - 10/2017
5	Leukocytosis (Pleocytosis) 01/2020 - 05/2012
4	Vision Disorders (Hemeralopia) 01/2022 - 06/2018
4	Headache (Headaches) 05/2021 - 01/2019
4	Central Nervous System Diseases (CNS Diseases) 11/2018 - 11/2014
4	Neoplasms (Cancer) 06/2018 - 04/2008
3	Ganglion Cysts (Ganglion) 01/2022 - 01/2017
3	Encephalomyelitis (Myeloencephalitis) 01/2020 - 08/2016
3	Disease Progression 07/2018 - 10/2015
3	Nervous System Diseases (Neurological Disorders) 01/2018 - 04/2012
3	Autoimmune Diseases (Autoimmune Disease) 01/2017 - 05/2003
3	Disorders of Excessive Somnolence (Hypersomnia) 12/2012 - 07/2009
2	Atrophy 01/2022 - 12/2017
2	Pain (Aches) 06/2021 - 09/2014
2	Cognitive Dysfunction 06/2021 - 10/2017
2	Epilepsy (Aura) 06/2021 - 11/2019
2	Respiratory Tract Infections (Respiratory Tract Infection) 05/2021 - 01/2019
2	Fatigue 01/2021 - 06/2015
2	Myasthenia Gravis 10/2020 - 11/2013
2	Hemorrhage 01/2020 - 01/2020
2	Meningitis 11/2019 - 10/2008
2	Progressive Multifocal Leukoencephalopathy 01/2018 - 01/2017
2	Polyneuropathies (Polyneuropathy) 01/2018 - 11/2013
2	Paraproteinemias (Monoclonal Gammopathy) 10/2016 - 01/2015
2	POEMS Syndrome (Syndrome, POEMS) 10/2016 - 01/2015
2	Hiccup (Hiccups) 01/2016 - 06/2013
2	Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental) 12/2015 - 10/2004
2	Meningoencephalitis 08/2014 - 12/2012
2	Inflammation (Inflammations) 02/2014 - 05/2012
2	Necrosis 06/2013 - 10/2004
2	Opticospinal Multiple Sclerosis 01/2011 - 02/2009
1	Nasopharyngitis 05/2021
1	Peripheral Nervous System Diseases (PNS Diseases) 03/2021
1	Alzheimer Disease (Alzheimer's Disease) 01/2021
1	Anti-N-Methyl-D-Aspartate Receptor Encephalitis 01/2021
1	Corticobasal Degeneration 01/2021
1	Gliosis 01/2021
1	Progressive Supranuclear Palsy (Steele Richardson Olszewski Syndrome) 01/2021
1	Tauopathies 01/2021
1	Wounds and Injuries (Trauma) 01/2021
1	Respiratory Tract Diseases (Respiratory Tract Disease) 10/2020
1	COVID-19 10/2020

Drug/Important Bio-Agent (IBA)

27	Myelin-Oligodendrocyte GlycoproteinIBA 01/2022 - 02/2014
27	AntibodiesIBA 08/2021 - 02/2009
26	Immunoglobulin G (IgG)IBA 03/2022 - 12/2004
15	AutoantibodiesIBA 05/2021 - 12/2004
12	Aquaporin 4IBA 01/2021 - 02/2009
9	Proteins (Proteins, Gene)FDA Link 06/2018 - 01/2005
8	Rituximab (Mabthera)FDA Link 04/2022 - 07/2011
8	Biomarkers (Surrogate Marker)IBA 01/2021 - 09/2010
7	Retinaldehyde (Retinal)IBA 01/2022 - 01/2016
7	eculizumab FDA Link 01/2022 - 01/2017
7	SteroidsIBA 03/2021 - 10/2014
5	Complement System Proteins (Complement)IBA 01/2021 - 01/2013
5	CytokinesIBA 01/2021 - 10/2004
5	Oligoclonal BandsIBA 01/2018 - 06/2004
5	ChemokinesIBA 11/2016 - 04/2004
4	Aquaporins (Water Channels)IBA 05/2021 - 05/2007
4	Methylprednisolone FDA LinkGeneric 07/2020 - 04/2012
4	AntigensIBA 08/2016 - 05/2007
4	InterferonsIBA 10/2012 - 10/2004
3	Interleukin-6 (Interleukin 6)IBA 01/2021 - 08/2014
3	anti-aquaporin 4 autoantibodyIBA 12/2017 - 03/2009
3	Monoclonal AntibodiesIBA 01/2017 - 11/2013
3	OrexinsIBA 12/2012 - 07/2009
2	Prednisolone (Predate)FDA LinkGeneric 04/2021 - 01/2021
2	Immunosuppressive Agents (Immunosuppressants)IBA 10/2020 - 01/2019
2	EnzymesIBA 01/2020 - 08/2007
2	Myelin Basic ProteinIBA 01/2020 - 03/2017
2	Glial Fibrillary Acidic ProteinIBA 01/2020 - 08/2014
2	AlbuminsIBA 01/2018 - 05/2012
2	Fingolimod Hydrochloride (FTY720)FDA Link 01/2018 - 03/2014
2	ChloridesIBA 01/2018 - 01/2018
2	Natalizumab (Tysabri)FDA Link 01/2017 - 11/2013
2	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 10/2016 - 01/2015
2	Thalidomide (Thalomid)FDA Link 10/2016 - 01/2015
2	Therapeutic UsesIBA 01/2011 - 02/2005
2	Codon (Codons)IBA 04/2008 - 11/2007
1	Endoplasmic Reticulum Chaperone BiPIBA 01/2022
1	BNT162 VaccineIBA 12/2021
1	COVID-19 VaccinesIBA 12/2021
1	VaccinesIBA 12/2021
1	Complement Inactivating AgentsIBA 05/2021
1	Myelin-Associated GlycoproteinIBA 01/2021
1	THK5351IBA 01/2021
1	Monoamine Oxidase (MAO)IBA 01/2021
1	Complement Membrane Attack Complex (Membrane Attack Complex)IBA 01/2021
1	N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA 01/2021

Therapy/Procedure

13	Therapeutics 04/2021 - 10/2004
2	Aftercare (After-Treatment) 12/2012 - 04/2012
2	Plasma Exchange 04/2012 - 05/2007
1	Secondary Prevention 01/2021
1	Immunotherapy 10/2020